Delivery may affect arterial elasticity in women.

نویسندگان

  • Masayoshi Hashimoto
  • Yoshitomo Miyamoto
  • Chikao Iwai
  • Yasuaki Matsuda
  • Eiji Hiraoka
  • Kenji Kanazawa
  • Kunihiro Nishimura
  • Daisuke Sugiyama
  • Kazuo Ito
  • Yukio Yamori
  • Hozuka Akita
چکیده

BACKGROUND Estrogen is considered to be cardioprotective, but estrogen replacement therapy for postmenopausal women has not shown results for either primary or secondary cardiovascular event prevention. During normal pregnancy, women have significantly higher levels of estrogen and it may be endogenous estrogen that helps prevent atherosclerosis. METHODS AND RESULTS The present cross-sectional study examined the association between pregnancy followed by delivery and clinical atherosclerosis using the brachial-ankle pulse wave velocity (PWV). A total of 2,560 women undergoing annual health screening at the Institute of Hyogo Prefecture Health Promotion Association in Japan were recruited. Pregnancy history (the age of menarche/menopause and the number of gravida/para), conventional coronary risk factors, and brachial-ankle PWV were recorded. Multivariate linear regression by stepwise selection analysis demonstrated that women who had 1 or more deliveries had a significantly lower PWV, independent of age and other conventional coronary risk factors. CONCLUSIONS Pregnancy followed by delivery may decrease arterial stiffness and prevent the progress of atherosclerosis in women. The contribution of such a pregnancy followed by delivery-related decrease in arterial stiffness to the reduction of cardiovascular disease in women should be further evaluated.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Arterial Elasticity, Strength, Fatigue, and Endurance in Older Women

Arterial health may influence muscle function in older adults. Study purpose was to determine whether arterial elasticity is related to strength, central and peripheral fatigue, fatigue at rest, and treadmill endurance. Subjects were 91 healthy women aged >60. Treadmill endurance and maximal oxygen uptake (VO2 max) were measured. Peripheral and central fatigue for the knee extensors were evalua...

متن کامل

Large and small arterial elasticity in healthy active and sedentary premenopausal women.

The purpose of this study was to compare large and small arterial elasticity in apparently healthy sedentary and recreationally active adult women, and to examine if age affects large and small arterial elasticity. This cross-sectional study consisted of 43 premenopausal women without overt cardiovascular disease (age = 43.4 ± 4.7 yrs; mean ± SD). The subjects were grouped into a sedentary grou...

متن کامل

Editorial Commentary Arterial Stiffness and Left Ventricular Diastolic Function Does Sex Matter?

Diastolic heart failure with preserved systolic ejection fraction is becoming a major health burden and is responsible for 50% of heart failure hospital admissions. Arterial hypertension is one of the most important risk factors for diastolic dysfunction; however, systolic and diastolic blood pressures are the 2 extreme points of the arterial waveform. Arterial stiffness/elasticity derived from...

متن کامل

Does Sex Matter?

Diastolic heart failure with preserved systolic ejection fraction is becoming a major health burden and is responsible for 50% of heart failure hospital admissions. Arterial hypertension is one of the most important risk factors for diastolic dysfunction; however, systolic and diastolic blood pressures are the 2 extreme points of the arterial waveform. Arterial stiffness/elasticity derived from...

متن کامل

Arterial stiffness and left ventricular diastolic function: does sex matter?

Diastolic heart failure with preserved systolic ejection fraction is becoming a major health burden and is responsible for 50% of heart failure hospital admissions. Arterial hypertension is one of the most important risk factors for diastolic dysfunction; however, systolic and diastolic blood pressures are the 2 extreme points of the arterial waveform. Arterial stiffness/elasticity derived from...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Circulation journal : official journal of the Japanese Circulation Society

دوره 73 4  شماره 

صفحات  -

تاریخ انتشار 2009